Hugo Ekitike could become the first Reds player since Daniel Sturridge in January 2013 to score in each of his first three games for the club.
Liverpool have netted 90 goals in 39 Premier League games under Slot so far, an average of 2.3 per match. That is the best ratio of any Reds boss in the top flight.
Newcastle have won their first home fixture of the campaign in all three previous seasons under Eddie Howe.
The Magpies have won each of their last three Premier League games on a Monday to nil, although all of those victories came away from home.
The Reds have not lost their first away match in any of the last 10 Premier League seasons (seven wins, three draws), since a 3-1 defeat at Manchester City in 2014-15.
Liverpool have scored 124 Premier League goals against Newcastle. Only the Reds (125 v Tottenham Hotspur) and Arsenal (125 v Everton) have netted more against a specific opponent in the competition.
Overall in league football, only against Aston Villa (348 in 194 games) have the Reds scored more than the 317 (in 176 matches) against Newcastle.
Newcastle have won six of their last seven league matches at home, losing 1-0 to Everton on the final day of 2024-25.
Bruno Guimaraes was the Magpies’ only ever-present in the league last season and has played in each of his team’s past 65 top-flight matches.
Jacob Murphy has 10 goal involvements in his last 12 Premier League appearances at St. James’ Park (five goals, five assists).
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